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價格：電議
所在地：北京
型號：96T
更新時間：2024-04-22
瀏覽次數：1462
公司地址：北京市海淀區廂黃旗2號樓1層4-179室
李小姐(女士)
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骨生化標志物ELISA試劑盒詳細介紹：
一.Anti-Human PTH (1-34) Antibody ELISA KitINTENDED USE This kit is intended for research use only in the qualitative detection of antibodies to human PTH (1-34) in humans or other animal models. Reference ranges and clinical utility have not been established. 二.Anti-Human PTH (1-34) Antibody ELISA Kit INTRODUCTION (rhPTH 1-34) is a recombinant human parathyroid hormone derivative consisting of the first 34 amino acids of the hormone. Teriparatide was approved as a drug by the FDA in 2002 and is sold by Eli Lilly & Co. under the brand name Forteo. Teriparatide is indicated for use in patients with osteoporosis. It is currently administered by injection and has an anabolic effect on bone, binding to the PTH/PTHrp Type 1 receptor with the same affinity as the intact molecule, PTH (1-84). This receptor activation results in a series of events leading to the formation of new trabecular and cortical bone. Research is continuing at pharmaceutical and biotech companies to pursue similar drugs and alternate delivery pathways.Immunogenicity for this drug, defined as the presence of antibodies to human PTH (1-34), was detected in 2.8% of women receiving teriparatide during the clinical trials of Forteo. The detection of these circulating antibodies may be of clinical relevance for the proper assessment of patients. |
免責聲明：以上所展示的[96T 人甲狀旁腺激素1-34 ELISA試劑盒]信息由會員[北京科瑞美科技有限公司]自行提供，內容的真實性、準確性和合法性由發布會員負責。
