產品簡介
"上海博耀生物銷售FABP4 Antibody #2120，CST原裝品質，價格優惠，訂購FABP4 Antibody #2120，詳情請咨詢銷售人員！產品詳細參數
產品說明
"上海博耀生物銷售
FABP4 Antibody #2120，CST原裝品質，價格優惠，訂購
FABP4 Antibody #2120，詳情請咨詢銷售人員！
產品詳細參數如下>>>>
產品名稱：FABP4 Antibody #2120
貨號：2120
品牌：CST(cell signaling)
抗體來源：Rabbit
克隆類型：
Polyclonal
規格：
| No. |
Size |
Price |
| 2120S |
100 ul (10 western blots) |
詢價 |
抗體應用：
| Applications |
Reactivity |
Sensitivity |
MW (kDa) |
Source |
| W |
M |
Endogenous |
15 |
Rabbit |
Applications Key:
W=Western Blotting
Reactivity Key:
M=Mouse
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on sequence homology.
特異性/敏感度：
FABP4 Antibody detects endogenous levels of total FABP4 protein.
來源及純化方法：
Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to the sequence of mouse FABP4. Antibodies are purified by peptide affinity chromatography.
抗體背景：
Fatty acid binding proteins (FABPs) bind to fatty acids and other lipids to function as cytoplasmic lipid chaperones (1). They participate in the transport of fatty acids and other lipids to various cellular pathways (2). The predominant fatty acid binding protein found in adipocytes is FABP4, also called adipocyte fatty acid binding protein or aP2. FABP4 is also expressed in macrophages (3). FABP4 knockout mice fed a high-fat and high-calorie diet become obese but develop neither insulin resistance nor diabetes, suggesting that this protein might be a link between obesity and insulin resistance and diabetes (4). Mice deficient in both FABP4 and ApoE show protection against atherosclerosis when compared with mice deficient only in ApoE (3). Mice carrying a FABP4 genetic variant exhibit both reduced FABP4 expression and a reduced potential for developing type 2 diabetes and coronary heart disease. A related study in humans indicated a similar pattern, suggesting that FABP4 may be a potential therapeutic target in the treatment of these disorders (1).
關鍵詞：CST，抗體，一抗{byao_back}{byao_back2}
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