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"上海博耀生物銷售Lamin A/C Antibody #2032，CST原裝品質(zhì)，價(jià)格優(yōu)惠，訂購(gòu)Lamin A/C Antibody #2032，詳情請(qǐng)咨詢銷售人員！產(chǎn)品
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"上海博耀生物銷售
Lamin A/C Antibody #2032，CST原裝品質(zhì)，價(jià)格優(yōu)惠，訂購(gòu)
Lamin A/C Antibody #2032，詳情請(qǐng)咨詢銷售人員！
產(chǎn)品詳細(xì)參數(shù)如下>>>>
產(chǎn)品名稱：Lamin A/C Antibody #2032
貨號(hào)：2032
品牌：CST(cell signaling)
抗體來(lái)源：Rabbit
克隆類型：
Polyclonal
規(guī)格：
| No. |
Size |
Price |
| 2032S |
100 ul (10 western blots) |
詢價(jià) |
抗體應(yīng)用：
| Applications |
Reactivity |
Sensitivity |
MW (kDa) |
Source |
| W IHC-P |
H M R (B) |
Endogenous |
28, 70 |
Rabbit |
Applications Key:
W=Western Blotting
IHC-P=Immunohistochemistry (Paraffin)
Reactivity Key:
H=Human
M=Mouse
R=Rat
B=Bovine
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on sequence homology.
特異性/敏感度：
Lamin A/C Antibody detects endogenous levels of total full length lamin A (and lamin C) (70 kDa), as well as the small fragment of lamin A (and lamin C) resulting from cleavage at aspartic acid 230 (28 kDa).
來(lái)源及純化方法：
Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Asp230 of human lamin A. Antibodies are purified by protein A and peptide affinity chromatography.
抗體背景：
Lamins are nuclear membrane structural components that are important in maintaining normal cell functions such as cell cycle control, DNA replication, and chromatin organization (1-3). Lamin A/C is cleaved by caspase-6 and serves as a marker for caspase-6 activation. During apoptosis, lamin A/C is specifically cleaved into a large (41-50 kDa) and a small (28 kDa) fragment (3,4). The cleavage of lamins results in nuclear disregulation and cell death (5,6).
關(guān)鍵詞：CST，抗體，一抗{byao_back}{byao_back2}
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