特別提示：包括重組人importinβ1(KPNB1)(核轉運受體蛋白)(輸入蛋白β1)在內，本公司的所有產品僅可用于科研實驗，嚴禁用于臨床醫療及其他非科研用途！
產品名稱：重組人im
portinβ1(KPNB1)(核轉運受體蛋白)(輸入蛋白β1)
英文名稱：Recombinant Human im
portin Subunit Beta-1
產品貨號：JN1588
產品規格：10μg|50μg|500μg|1mg
本品由我們的大腸桿菌表達系統制備而成，目的基因編碼的Met1-Ala876在N端含有His標簽。
KPNB1質量控制：＞95%(還原性SDS-PAGE)
KPNB1制劑：液體
KPNB1保存：收到貨后請置于-20℃，可保存6個月，避免反復凍融。
關于KPNB1：
im
portin subunit beta-1(KPNB1) is a member of the im
portin beta family. KPNB1 co
ntains 1 im
portin N-terminal domain and 19 HEAT repeats. It is involved in nucleocytoplasmic transport, a signal- and energy-dependent process, takes place through nuclear pore complexes embedded in the nuclear envelope. Its functions in nuclear protein im
port, either in association with an adapter protein, like an im
portin-alpha subunit, which binds to nuclear localization signals (NLS) in cargo substrates, or by acting as auto
nomous nuclear transport receptor. The im
port of proteins co
ntaining a classical nuclear localization signal (NLS) requires the NLS im
port receptor, a heterodimer of im
portin alpha and beta subunits. Each of these subunits is part of the karyopherin family of proteins. im
portin alpha binds the NLS-co
ntaining cargo in the cytoplasm and im
portin beta docks the complex at the cytoplasmic side of the nuclear pore complex. It mediates auto
nomously the nuclear im
port of ribosomal proteins RPL23A, RPS7 and RPL5.
根據您的關注的
重組人importinβ1(KPNB1)(核轉運受體蛋白)(輸入蛋白β1)，重組核轉運受體蛋白，rim
portinβ1，rKPNB1，重組im
portin Subunit Beta-1，重組人im
portin Subunit Beta-1，重組人核轉運受體蛋白，Recombinant Human im
portin Subunit Beta-1，重組im
portinβ1，rhim
portinβ1，重組人im
portinβ1，重組人輸入蛋白β1，重組KPNB1，重組人KPNB1，重組輸入蛋白β1，rhKPNB1，您可能還對以下產品有需求：
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貨號
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名稱
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規格
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|
JN0224
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重組人VEGF-A(VEGF165)
|
10μg|50μg|500μg|1mg
|
|
JN0431
|
重組小鼠干擾素γ
|
10μg|50μg|500μg|1mg
|
|
JN1898
|
重組人甲狀旁腺素(PTH)
|
10μg|50μg|500μg|1mg
|
|
JN1925
|
重組人β-防御素4A
|
10μg|50μg|500μg|1mg
|
|
JN1970
|
重組人子宮球蛋白相關蛋白1(UGRP1)
|
10μg|50μg|500μg|1mg
|
|
JN0609
|
重組人PDILT
|
10μg|50μg|500μg|1mg
|
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關注
重組人importinβ1(KPNB1)(核轉運受體蛋白)(輸入蛋白β1)，重組核轉運受體蛋白，rim
portinβ1，rKPNB1，重組im
portin Subunit Beta-1，重組人im
portin Subunit Beta-1，重組人核轉運受體蛋白，Recombinant Human im
portin Subunit Beta-1，重組im
portinβ1，rhim
portinβ1，重組人im
portinβ1，重組人輸入蛋白β1，重組KPNB1，重組人KPNB1，重組輸入蛋白β1，rhKPNB1的同時，為您推薦更多您可能感興趣的產品：
名稱：重組人SHH(音猬因子)
貨號：JN0229
規格：10μg|50μg|500μg|1mg
本品由我們的大腸桿菌表達系統制備，目的基因編碼的Cys24-Gly197表達純化而來。
SHH質量控制：＞95%(還原性SDS-PAGE)。
SHH制劑：凍干品
SHH保存：
凍干蛋白可在-20℃長期保存，室溫也可穩定保存3周。
復溶蛋白溶液可在4～7℃保存2～7天。
復溶后建議分裝凍存在-20℃，可保存3個月，應避免反復凍融。
SHH復溶：
1、試劑開蓋前請先離心。
2、復溶濃度應大于100 μg/ml.
3、凍干蛋白溶于ddH2O中
4、復溶后根據使用量分裝保存，避免反復凍融。
關于SHH：
So
nic Hedgehog Homolog (SHH) belo
ngs to a three-protein family called hedgehog. The other two family members are Indian Hedgehog (IHH) and Desert Hedgehog (DHH). Hedgehog proteins are key signaling molecules in embryo
nic development. SHH is expressed in various embryo
nic tissues and plays critical roles in regulating the patterning of many systems, such as limbs and brain. SHH also plays an im
portant role in adult, including the division of adult stem cells and the development of certain cancers and other diseases. Human SHH is expressed as a 45kDa precursor, and undergoes a series of processing during secretion. After the removal of the signal peptide, a protease within the C-terminal domain catalyzes the cleavage of SHH into a 20 kDa N-terminal signaling domain (SHH-N) and a 25 kDa C-terminal domain (SHH-C). SHH-N has the “all signaling” capability. SHH-N binds to the 12 pass transmembrane protein Patched (Ptc) on cell surface, which releases the repression of the activity of Smoothened (Smo), a G-protein coupled receptor, by Ptc.
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